Browsing by Author "Bourgain, Catherine"
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Are common disease susceptibility alleles the same in outbred and founder populations?
Newman, Dina; Hoffjan, Sabine; Bourgain, Catherine; Abney, Mark; Nicolae, Raluca; Profits, Elle; Grow, Michael; Walker, Karen; Steiner, Lori; Parry, Rodney; Reynolds, Rebecca; McPeek, Mary; Cheng, Suzanne; Ober, Carole (Nature Publishing Group: European Journal of Human Genetics, 2004-07)Founder populations have been the subjects of complex disease studies because of their decreased genetic heterogeneity, increased linkage disequilibrium and more homogeneous environmental exposures. However, it is possible ...