Browsing by Subject "Homology"

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    • Homology-based annotation yields 1,042 new candidate genes in the Drosophila melanogaster genome 

      Gopal, Shuba; Schroeder, Mark; Pieper, Ursula; Sczyrba, Alexander; Aytekin-Kurban, Gulriz; Bekiranov, Stefan; Fajardo, Eduardo; Eswar, Narayanan; Sanchez, Roberto; Sali, Andrej; Gaasterland, Terry (Nature Publishing Group: Nature Genetics, 2001-03)
      The approach to annotating a genome critically affects the number and accuracy of genes identified in the genome sequence. Genome annotation based on stringent gene identification is prone to underestimate the complement ...