Browsing by Subject "Transcription"
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Repression of HPV16 early region transcription by the E2 protein
(Elsevier: Virology, 2006-07-20)HPV16 DNA is often integrated in cancers, disrupting the E1 or E2 genes. E2 can repress the E6/E7 promoter, but other models have been proposed to explain why integration promotes malignant progression. E1 and E2 are ...