Browsing Meeting minutes, announcements and publications from RIT Colleges by Subject "Genome annotation"

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    • Homology-based annotation yields 1,042 new candidate genes in the Drosophila melanogaster genome 

      Gopal, Shuba; Schroeder, Mark; Pieper, Ursula; Sczyrba, Alexander; Aytekin-Kurban, Gulriz; Bekiranov, Stefan; Fajardo, Eduardo; Eswar, Narayanan; Sanchez, Roberto; Sali, Andrej; Gaasterland, Terry (Nature Publishing Group: Nature Genetics, 2001-03)
      The approach to annotating a genome critically affects the number and accuracy of genes identified in the genome sequence. Genome annotation based on stringent gene identification is prone to underestimate the complement ...

    • An organism-specific method to rank predicted coding regions in Trypanosoma brucei 

      Gopal, Shuba; Cross, George; Gaasterland, Terry (Oxford University Press: Nucleic Acids Research, 2003)
      Genome annotation in differently evolved organisms presents challenges because the lack of sequence-based homology limits the ability to determine the function of putative coding regions. To provide an alternative to ...