Now showing items 1-2 of 2

    • Are common disease susceptibility alleles the same in outbred and founder populations? 

      Newman, Dina; Hoffjan, Sabine; Bourgain, Catherine; Abney, Mark; Nicolae, Raluca; Profits, Elle; Grow, Michael; Walker, Karen; Steiner, Lori; Parry, Rodney; Reynolds, Rebecca; McPeek, Mary; Cheng, Suzanne; Ober, Carole (Nature Publishing Group: European Journal of Human Genetics, 2004-07)
      Founder populations have been the subjects of complex disease studies because of their decreased genetic heterogeneity, increased linkage disequilibrium and more homogeneous environmental exposures. However, it is possible ...
    • Genetic variation in immunoregulatory pathways and atopic phenotypes in infancy 

      Hoffjan, Sabine; Ostrovnaja, Irina; Nicolae, Dan; Newman, Dina; Nicolae, Raluca; Gangnon, Ronald; Steiner, Lori; Walker, Karen; Reynolds, Rebecca; Greene, Deborah; Mirel, Daniel; Gern, James; Lemanske, Robert; Ober, Carole (Elsevier: The Journal of Allergy and Clinical Immunology, 2004-03)
      Background: Asthma is a chronic respiratory disease that often originates in early childhood. Although candidate gene studies have identified many potential asthma susceptibility genes in adult populations, few have studied ...