Now showing items 1-8 of 8

    • 5-Bromodeoxyuridine does not affect development of the sea urchin, Arbacia punctulata 

      Evans, Irene; Gross, Paul (Elsevier: Experimental Cell Research, 1978-06)
      Development of Arbacia punctulata embryos in the presence of bromodeoxyuridine (BUdR) was investigated under conditions which allowed about 20% substitution of BUdR for thymidine residues in DNA. Development was essentially ...
    • Apoptosis of the hyaloid vessels in vivo and in vitro in the newborn rat eye 

      Evans, Irene; Curanovic, D.; Bucher, B.; Roberts, S. (Association for Research in Vision and Ophthalmology: Investigative Ophthalmology and Visual Science, 2004)
      Purpose: In the newborn rat eye, the hyaloid vasculature persists after birth and regresses postnatally. Several studies have shown that apoptosis plays a role in this regression although the mechanism is unknown. Apoptosis ...
    • Chemical carcinogen in vitro testing: a method for sizing cell nuclei in the nuclear enlargement assay 

      Finch, Robert; Evans, Irene; Bosmann, H. Bruce (Elsevier: Toxicology, 1980)
      The observation that cells often respond to carcinogens by nuclear enlargement has suggested that this property might be useful to develop a short-term screening test for such compounds. Previous methods for detecting ...
    • Confocal imaging of the regression of the rat hyaloid vasculature 

      Evans, Irene; Donahue, Margret (Association for Research in Vision and Ophthalmology: Investigative Ophthalmology and Visual Science, 2006)
      Purpose: Regression of the hyaloid/fetal vessel system was studied in the newborn rat using confocal microscopy. The hyaloid vasculature composed of the hyaloid artery (HA), vasa hyaloidia propia (VHP), tunica vasculosa ...
    • The microarray revolution 

      Brewster, Jay; Beason, K.; Eckdahl, Todd; Evans, Irene (Elsevier: Biochemistry and Molecular Biology Education, 2004-07)
      In recent years, microarray analysis has become a key experimental tool, enabling the analysis of genome-wide patterns of gene expression. This review approaches the microarray revolution with a focus upon four topics: 1) ...
    • Nutrient deprivation may be a poor inducer of apoptosis in the newborn rat eye 

      Evans, Irene; Adams, S. (Association for Research in Vision and Ophthalmology: Investigative Ophthalmology and Visual Science, 2003)
      Purpose: The hyaloid vasculature of the newborn rat eye persists after birth and regresses postnatally. One hypothesis is that regression occurs due to a decrease in blood flow to the hyaloid after retinal development and ...
    • Tree eye endothelial cells undergo apoptosis after serum starvation 

      Evans, Irene; Van Winkle, B. (Association for Research in Vision and Ophthalmology: Investigative Ophthalmology and Visual Science, 2002)
      Purpose: Several explanations have been suggested for why endothelial cells undergo apoptosis in the regressing blood vessels found in the newborn rat eye. These explanations hypothesize that apoptosis occurs due to lack ...
    • Visualization of the regression of the hyaloid vasculature and retinal vessel formation in the newborn rat using FITC/Dextran 

      Evans, Irene; Bucher, B.; Ocon, A.; Tapley, J. (Association for Research in Vision and Ophthalmology: Investigative Ophthalmology and Visual Science, 2005)
      Purpose: The regression of the pupillary membrane and hyaloid vasculature of the eye was observed in the newborn rat from postpartum days 1–36 by injection of FITC–dextran. We also observed the development of the retinal ...