Browsing Citations Only by Author "Friedman, Alan"
Now showing items 1-19 of 19
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Apparent cytochrome gene dose effects in F-lac and F-gal heterogenotes of Escherichia coli.
Shipp, W.; Piotrowski, M.; Friedman, Alan (Elsevier: Archives of Biochemistry and Biophysics, 1972-06)The levels of b- and c-type cytochromes and cytochromes a1 and a2 are elevated in a partial diploid strain of E. coli carrying the F2-gal episome under a variety of different growth conditions. Only the levels of b- and ... -
Characterization of dipyridophenazine complexes of ruthenium( 11): the light switch effect as a function of nucleic acid sequence and conformation
Jenkins, Yonchu; Friedman, Alan; Turro, Nicholas; Barton, Jacqueline (The American Chemical Society: Biochemistry, 1992-11-10)Spectroscopic parameters for two novel ruthenium complexes on binding to nucleic acids of varying sequences and conformations have been determined. These complexes, R~(bpy)~dppz~+ and Ru(phen)2dppz2+ (bpy = 2,2’-bipyridine; ... -
Evaluation of human viral disease transmission through plasma products.
Heldebrant, C.; Friedman, Alan; Fedor, E. (Karger: Developments in Biologicals, 1987) -
Evaluation of two viral inactivation methods for the preparation of safer factor VIII and factor IX concentrates
Heldebrant, C.; Gomperts, E.; Kasper, C.; McDougal, J.; Friedman, Alan; Hwang, D.; Muchmore, E.; Jordan, S.; Miller, R.; Sergis-Davenport, E. (Blackwell Publishing: Transfusion, 1985-11)We report here the results of our evaluation of two procedures to eliminate viruses in factor VIII and factor IX coagulation factor concentrates. Both procedures were equally effective in the in vitro destruction of marker ... -
Horseradish peroxidase Phe172-->Tyr mutant. Sequential formation of compound I with a porphyrin radical cation and a protein radical.
Miller, Vaughn; Goodin, David; Friedman, Alan; Hartmann, Christa; Ortiz de Montellano, Paul (Waverly: Journal of Biological Chemistry, 1995-08-04)A gene coding for the F172Y mutant of horseradish peroxidase isozyme C (HRP) has been constructed and expressed in both Spodoptera frugiperda (SF-9) and Trichoplusia ni egg cell homogenate (HighFive) cells. Homology modeling ... -
A mechanism for the oxidation of glutathione to glutathione disulfide with organotellurium(IV) and organoselenium(IV) compounds. A stepwise process with implications for photodynamic therapy and other oxidative chemotherapy
Detty, Michael; Friedman, Alan; Oseroff, Alan (The American Chemical Society: The Journal of Organic Chemistry, 1994-12-30)The reactions of telluroxides or their hydrates 3-5 with glutathione to give telluropyrylium dyes 1, 2 or diphenyl telluride, respectively, and glutathione disulfide have at least two discrete steps. A fast reaction, which ... -
Molecular “light switch” for DNA: Ru(bpy)2(dppz)2+
Friedman, Alan; Chambron, Jean-Claude; Sauvage, Jean-Pierre; Turro, Nicholas; Barton, Jacqueline (The American Chemical Society: Journal of the American Chemical Society, 1990-06-06) -
Origins of high sequence selectivity: a stopped-flow kinetics study of DNA/RNA hybridization by duplex- and triplex-forming oligonucleotides
Wang, Shaohui; Friedman, Alan; Kool, Eric (The American Chemical Society: Biochemistry, 1995-08-01)Stopped-flow UV kinetics and thermal denaturation experiments are used to examine the origins of high sequence selectivity and binding affinity of circular triplex-forming oligonucleotides with single-stranded DNA/RNA ... -
Oxidation of telluropyrylium dyes with ozone, chlorine, and bromine. Differing regiochemical and kinetic behavior with respect to oxidations of oxygen-, sulfur-, and selenium-containing dyes
Detty, Michael; Friedman, Alan (The American Chemical Society: Organometallics, 1994-02)Oxidations of telluropyrylium dyes 1-3 with ozone in water, chlorine in carbon tetrachloride, or bromine in carbon tetrachloride gave second-order rate constants of greater-than-or-equal-to 10(9) L mol-1 s-1 using stopped-flow ... -
Palladium/hydrogen catalyzed alcoholysis of benzylsilanes
Pitt, Colin; Friedman, Alan; Rector, Douglas; Wani, Mansukh (Elsevier: Journal of Organometallic Chemistry, 1976)Certain benzylsilanes are converted to methoxy or ethoxysilanes and toluene when treated with methanol or ethanol in the presence of hydrogen and catalytic amounts of palladium on charcoal. The reaction is promoted by a ... -
Photoisomerization of the ruthenium cluster HRu3(CO)10(.mu.-COCH3), an unprecedented oxygen-to-carbon alkyl migration
Friedman, Alan; Ford, Peter (The American Chemical Society: Journal of the American Chemical Society, 1986-11-26) -
Photoreactions of docosylcarbonyloctairidate(2-). Homolytic cleavage of an unsupported metal-metal bond linking two tetrahedral iridium carbonyl clusters
Vandenberg, David; Friedman, Alan; Ford, Peter (The American Chemical Society: Inorganic Chemistry, 1988-02-28) -
Photoreactions of the triruthenium cluster HRu3(CO)10 (.mu.-COCH3). Isomerization of the bridging alkylidyne ligand and competing ligand substitutions
Friedman, Alan; Ford, Peter (The American Chemical Society: Journal of the American Chemical Society, 1989-01-18)Irradiation of the title compound HRu3(CO)10(u-COCH3) (A) in hydrocarbon solution under CO leads to the formation of the bridging u,n2 acyl isomer HRu3(CO)10(u,n2-C(O)CH3) (B). Quantum yields for isomerization phi-i were ... -
Photoreactions of the triruthenium cluster Ru3(CO)12 and substituted analogs
Derosiers, Marc; Wink, David; Trautman, Ray; Friedman, Alan; Ford, Peter (The American Chemical Society: Journal of the American Chemical Society, 1986-04-16)Reported is a comprehensive investigation of the medium, ligand, and wavelength effects on the quantum yields and flash photolysis kinetics for the photofragmentation and photosubstitution reactions of the trinuclear ... -
Positive halogens from halides and hydrogen peroxide with organotellurium catalysts
Detty, Michael; Zhou, Feng; Friedman, Alan (The American Chemical Society: Journal of the American Chemical Society, 1996-01-17)The oxidations of sodium bromide, sodium chloride, and sodium iodide to positive halogen with hydrogen peroxide in two-phase systems of dichloromethane and pH 6 phosphate buffer were catalyzed by organotellurium catalysts ... -
Pressure effects on the photophysical properties of the platinum(II) dimer Pt2(POP)44- (POP = .mu.-.eta.2-H2P2O52-) and related d8-d8 dinuclear complexes in solution
Fetterolf, Monty; Friedman, Alan; Yang, Yun Yen; Offen, Henry; Ford, Peter (The American Chemical Society: Journal of Physical Chemistry, 1988-06-30)The effect of hydrostatic pressure (0.1-300 MPa) upon phosphorescence lifetimes in fluid solution has been examined for four dinuclear d8-d8 transition-metal complexes: A, Pt2(POP)44- (POP = u-n2-H2P2O52-); B, Rh2(br)42+ ... -
Stepwise mechanism for oxidative addition of bromine to organoselenium(II) and organotellurium(II) compounds
Detty, Michael; Friedman, Alan; McMillan, Martin (The American Chemical Society: Organometallics, 1994-08)The oxidative-addition reactions of bromine (5 x 10(-4) or 5 x 10(-5) M) to phenyl selenide (1), phenyl telluride (2), 2,6-di-tert-butylselenopyran-4-one (3), 2,6-di-tert-butyltelluropyran-4-one (4), 2,6-diphenyltelluropyran-4-one ... -
Stepwise mechanism for oxidative addition of iodine to organotellurium(II) compounds as observed by stopped-flow spectroscopy
Detty, Michael; Friedman, Alan; McMillan, Martin (The American Chemical Society: Organometallics, 1995-03)The reaction of iodine with a series of diorgano tellurides was monitored by stopped-flow spectroscopy. For dihexyl telluride (11, diphenyl telluride (2), di-p-anisyl telluride (31, and phenyl 2-((dimethylamino)methyl)phenyl ... -
The total synthesis and anti-fertility activity of 6-silasteroids
Pitt, Colin; Friedman, Alan; Rector, Douglas; Wani, Mansukh (Elsevier: Tetrahedron, 1975)4,4-Dimethyl-6-methoxy-4-sila-1-tetralone (2) was prepared by a modified literature procedure and converted to 3-methoxy-6,6-dimethyl-6-silaestra-1,3,5(10),8,14-pentaen-17β-yl acetate (5c). Catalytic hydrogenation of 5c ...