Browsing Citations Only by Author "Goldman, David"

Now showing items 1-3 of 3

    • Allelic variation at alcohol metabolism genes (ADH1B, ADH1C, ALDH2) and alcohol dependence in an American Indian population 

      Mulligan, Connie; Robin, Robert; Osier, Michael; Sambuughin, Nyamkhishig; Goldfarb, Lev; Kittles, Rick; Hesselbrock, Diane; Goldman, David; Long, Jeffrey (Springer: Human Genetics, 2003-09)
      Enzymes encoded by two gene families, alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH), mediate alcohol metabolism in humans. Allelic variants have been identified that alter metabolic rates and influence risk ...

    • A global perspective on genetic variation at the ADH genes reveals unusual patterns of linkage disequilibrium and diversity 

      Osier, Michael; Pakstis, Andrew; Soodyall, Himla; Comas, David; Goldman, David; Odunsi, Adekunle; Okonofua, Friday; Parnas, Josef; Schulz, Leslie; Bertranpetit, Jaume; Bonne-Tamir, Batsheva; Lu, Ru-Band; Kidd, Judith; Kidd, Kenneth (University of Chicago Press: American Journal of Human Genetics, 2002-07)
      Variants of different Class I alcohol dehydrogenase (ADH) genes have been shown to be associated with an effect that is protective against alcoholism. Previous work from our laboratory has shown that the two sites showing ...

    • Proline-threonine substitution in codon 351 of ADH1C is common in Native Americans. 

      Osier, Michael; Pakstis, Andrew; Goldman, David; Edenberg, Howard; Kidd, Judith; Kidd, Kenneth (Blackwell: Alcoholism: Clinical & Experimental Research, 2002-12)
      Background: The alcohol dehydrogenase (ADH) genes have been repeatedly associated with protection against alcoholism. Until now, only four protein coding variants have been identified (ADH1C Arg271Gln, Ile349Val, ADH1B ...