Now showing items 1-3 of 3

    • ALFRED: An allele frequency database for anthropology 

      Osier, Michael; Cheung, Kei-Hoi; Kidd, Judith; Pakstis, Andrew; Miller, Perry; Kidd, Kenneth (Wiley: American Journal of Physical Anthropology, 2002-09)
      The deluge of data from the human genome project (HGP) presents new opportunities for molecular anthropologists to study human variation through the promise of vast numbers of new polymorphisms (e.g., single nucleotide ...
    • A global perspective on genetic variation at the ADH genes reveals unusual patterns of linkage disequilibrium and diversity 

      Osier, Michael; Pakstis, Andrew; Soodyall, Himla; Comas, David; Goldman, David; Odunsi, Adekunle; Okonofua, Friday; Parnas, Josef; Schulz, Leslie; Bertranpetit, Jaume; Bonne-Tamir, Batsheva; Lu, Ru-Band; Kidd, Judith; Kidd, Kenneth (University of Chicago Press: American Journal of Human Genetics, 2002-07)
      Variants of different Class I alcohol dehydrogenase (ADH) genes have been shown to be associated with an effect that is protective against alcoholism. Previous work from our laboratory has shown that the two sites showing ...
    • Proline-threonine substitution in codon 351 of ADH1C is common in Native Americans. 

      Osier, Michael; Pakstis, Andrew; Goldman, David; Edenberg, Howard; Kidd, Judith; Kidd, Kenneth (Blackwell: Alcoholism: Clinical & Experimental Research, 2002-12)
      Background: The alcohol dehydrogenase (ADH) genes have been repeatedly associated with protection against alcoholism. Until now, only four protein coding variants have been identified (ADH1C Arg271Gln, Ile349Val, ADH1B ...