| dc.contributor.author | Neenan, J. | en_US |
| dc.contributor.author | Opitz, S. | en_US |
| dc.contributor.author | Cooke, C. | en_US |
| dc.contributor.author | Morrill, Terence | en_US |
| dc.contributor.author | Eckel, L. | en_US |
| dc.contributor.author | Ussery, M. | en_US |
| dc.date.accessioned | 2006-07-19T18:38:40Z | en_US |
| dc.date.available | 2006-07-19T18:38:40Z | en_US |
| dc.date.issued | 1996-06-18 | en_US |
| dc.identifier.citation | Bioorganic and Medicinal Chemistry Letters 6N12 (1996) 1381-1386 | en_US |
| dc.identifier.issn | 0960-894X | en_US |
| dc.identifier.uri | http://hdl.handle.net/1850/2138 | en_US |
| dc.description.abstract | Selective borohydride reduction of adenosine dialdehyde (1) gave the known adenosine 2'-monoaldehyde (2). Reaction of 1 with N,N'-diphenylethylenediamine, followed by reduction and deblocking gave adenosine 3'-monoaldehyde (5), a new compound. Unlike 2, compound 5 inhibited S-AdoHcy hydrolase and showed antiviral activity in vitro. | en_US |
| dc.format.extent | 37365 bytes | en_US |
| dc.format.mimetype | application/pdf | en_US |
| dc.language.iso | en_US | en_US |
| dc.publisher | Elsevier: Bioorganic and Medicinal Chemistry Letters | en_US |
| dc.subject | Antiviral activity in vitro | en_US |
| dc.title | Adenosine dialdehyde analogs I: regioselective synthesis of adenosine monoaldehydes | en_US |
| dc.type | Abstract | en_US |
| dc.identifier.url | http://dx.doi.org/10.1016/0960-894X(96)00234-X | |
