dc.contributor.advisor | Tumor viruses | en_US |
dc.contributor.author | Ludlow, John | en_US |
dc.contributor.author | Skuse, Gary | en_US |
dc.date.accessioned | 2006-08-29T13:59:42Z | en_US |
dc.date.available | 2006-08-29T13:59:42Z | en_US |
dc.date.issued | 1995-02 | en_US |
dc.identifier.citation | Virus Research 35N2 (1995) 113-121 | en_US |
dc.identifier.issn | 0168-1702 | en_US |
dc.identifier.uri | http://hdl.handle.net/1850/2549 | en_US |
dc.description.abstract | The purpose of this review is to bring attention to some additional work in the tumor virus/tumor suppressor field which may have been overshadowed by reports describing adenovirus, SV40, and HPV oncoprotein binding to pRB and p53. The data reviewed herein provide further support for the model that a common mechanism by which DNA tumor viruses transform cells involves inactivation of cellular proteins which function as negative regulators of cell growth. | en_US |
dc.description.sponsorship | Research in these laboratories is supported by NIH grants CA56940 (J.W.L.), CA55173 (G.R.S.), and Cancer Center Core Grant CA11198 awarded to the late Robert A. Cooper Jr. | en_US |
dc.format.extent | 37365 bytes | en_US |
dc.format.mimetype | application/pdf | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | Elsevier: Virus Research | en_US |
dc.subject | Oncoproteins | en_US |
dc.subject | Tumor suppressors | en_US |
dc.title | Viral oncoprotein binding to PRB, P107, P130, AND P300 | en_US |
dc.type | Article | en_US |
dc.identifier.url | http://dx.doi.org/10.1016/0168-1702(94)00094-S | |