| dc.contributor.author | Maggelakis, Sophia | en_US |
| dc.contributor.author | Savakis, Andreas | en_US |
| dc.date.accessioned | 2007-10-10T14:19:13Z | en_US |
| dc.date.available | 2007-10-10T14:19:13Z | en_US |
| dc.date.issued | 1999-01 | en_US |
| dc.identifier.citation | Mathematical and Computer Modelling 29N2 (1999) 91-97 | en_US |
| dc.identifier.issn | 0895-7177 | en_US |
| dc.identifier.uri | http://hdl.handle.net/1850/5064 | en_US |
| dc.description | The file associated with this article includes the abstract only. | en_US |
| dc.description.abstract | A mathematical model based on diffusion equations is presented, which directly relates the production of Vascular Endothelial Growth Factor (VEGF) in the retina to oxygen concentration and consumption, the capillary density growth to VEGF production and concentration, and the oxygen concentration to the growth of capillary density. The effects of local neovascularization on local oxygenation, which in turn affects the vascularization process resulting in biological feedback, are examined. | en_US |
| dc.description.sponsorship | We would like to express our gratitude to the two anonymous reviewers for their constructive comments, particularly on the steady state behavior of the system, which improved the overall quality of the paper. | en_US |
| dc.language.iso | en_US | en_US |
| dc.publisher | Elsevier Science B.V. | en_US |
| dc.relation.ispartofseries | vol. 29 | en_US |
| dc.relation.ispartofseries | no. 2 | en_US |
| dc.subject | Capillary growth | en_US |
| dc.subject | Retinal neovascularization | en_US |
| dc.subject | Vascular endothelial growth factor (VEGF) | en_US |
| dc.title | A mathematical model of retinal neovascularization | en_US |
| dc.type | Abstract | en_US |
