Now showing items 1-2 of 2

    • A computational investigation of kinetoplastid trans-splicing 

      Gopal, Shuba; Awadalla, Saria; Gaasterland, Terry; Cross, George (BioMed Central: Genome Biology, 2005-10-17)
      Trans-splicing is an unusual process in which two separate RNA strands are spliced together to yield a mature mRNA. We present a novel computational approach which has an overall accuracy of 82% and can predict 92% of known ...
    • An organism-specific method to rank predicted coding regions in Trypanosoma brucei 

      Gopal, Shuba; Cross, George; Gaasterland, Terry (Oxford University Press: Nucleic Acids Research, 2003)
      Genome annotation in differently evolved organisms presents challenges because the lack of sequence-based homology limits the ability to determine the function of putative coding regions. To provide an alternative to ...