Browsing Meeting minutes, announcements and publications from RIT Colleges by Author "Abney, Mark"
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Are common disease susceptibility alleles the same in outbred and founder populations?
Newman, Dina; Hoffjan, Sabine; Bourgain, Catherine; Abney, Mark; Nicolae, Raluca; Profits, Elle; Grow, Michael; Walker, Karen; Steiner, Lori; Parry, Rodney; Reynolds, Rebecca; McPeek, Mary; Cheng, Suzanne; Ober, Carole (Nature Publishing Group: European Journal of Human Genetics, 2004-07)Founder populations have been the subjects of complex disease studies because of their decreased genetic heterogeneity, increased linkage disequilibrium and more homogeneous environmental exposures. However, it is possible ... -
Genome-wide association study identifies ITGB3 as a QTL for whole blood serotonin
Weiss, Lauren; Veenstra-VanderWeele, Jeremy; Newman, Dina; Kim, Soo-Jeong; Dytch, Harvey; McPeek, Mary; Cheng, Suzanne; Ober, Carole; Cook, Edwin Jr.; Abney, Mark (Nature Publishing Group: European Journal of Human Genetics, 2004-11)Serotonin has been implicated in common disorders involving the central nervous, gastrointestinal, cardiovascular, and pulmonary systems. We describe the first genome-wide screen to identify quantitative trait loci (QTLs) ... -
The importance of genealogy in determining genetic associations with complex traits
Newman, Dina; Abney, Mark; McPeek, Mary; Ober, Carole; Cox, Nancy (University of Chicago Press: American Journal of Human Genetics, 2001-11) -
Major loci influencing serum triglyceride levels on 2q14 and 9p21 localized by homozygosity-by-descent mapping in a large Hutterite pedigree
Newman, Dina; Abney, Mark; Dytch, Harvey; Parry, Rodney; McPeek, Mary; Ober, Carole (Oxford University Press: Human Molecular Genetics, 2003-01-15)Serum triglyceride (TG) level is a well-known risk factor for cardiovascular disease, a leading cause of morbidity and mortality in Western countries. Although genome-wide scans for TG have been conducted in several ...