Browsing Meeting minutes, announcements and publications from RIT Colleges by Author "Pancrazio, Joseph"
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Cell-based sensor microelectrode array characterized by imaging x-ray photoelectron spectroscopy, scanning electron microscopy, impedance measurements, and extracellular recordings
Jung, D.; Cuttino, David; Pancrazio, Joseph; Manos, Patricia; Cluster, T.; Sathanoori, R.; Aloi, L.; Coulombe, M.; Czarnaski, M.; Borkholder, David; Kovacs, Gregory; Bey, Paul Jr.; Stenger, David; Hickman, J. (American Vacuum Society, 1998-05)We are developing a cell-based biosensor consisting of a planar microelectrode array that allows detection of extracellular potentials and their modulation in the presence of toxins or other active agents. To improve ... -
Description and demonstration of a CMOS amplifier-based-system with measurement and stimulation capability for bioelectrical signal transduction
Pancrazio, Joseph; Bey, Paul Jr.; Loloee, Arash; Manne, SubbaRao; Chao, Hui-Chuan; Howard, Lorn; Gosney, W. Milton; Borkholder, David; Kovacs, Gregory; Manos, Patricia; Cuttino, David; Stenger, David (Elsevier www.elsevier.com/locate/bios, 1998-10)An extracellular recording system incorporating an electrode array and an amplifier/stimulator CMOS chip is described and characterized. Important features of this custom VLSI chip include 16 instrumentation amplifiers ... -
Development and application of cell-based biosensors
Pancrazio, Joseph; Whelan, J.; Borkholder, David; Ma, W.; Stenger, David (Springer, 1999)Biosensors incorporate a biological sensing element that converts a change in an immediate environment to signals conducive for processing. Biosensors have been implemented for a number of applications ranging from ... -
Portable cell-based biosensor system for toxin detection
Pancrazio, Joseph; Bey, Paul Jr.; Cuttino, David; Kusel, Julian; Borkholder, David; Shaffer, Kara; Kovacs, Gregory; Stenger, David (Elsevier www.elsevier.com/locate/sensorb, 1998-12)A portable cell-based biosensor has been developed and characterized. The prototype system relies on extracellular recording from excitable cells cultured over an array of platinized gold microelectrodes. Extracellular ...