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Genome-wide association study identifies ITGB3 as a QTL for whole blood serotonin
(Nature Publishing Group: European Journal of Human Genetics, 2004-11)
Serotonin has been implicated in common disorders involving the central nervous, gastrointestinal, cardiovascular, and pulmonary systems. We describe the first genome-wide screen to identify quantitative trait loci (QTLs) ...
Are common disease susceptibility alleles the same in outbred and founder populations?
(Nature Publishing Group: European Journal of Human Genetics, 2004-07)
Founder populations have been the subjects of complex disease studies because of their decreased genetic heterogeneity, increased linkage disequilibrium and more homogeneous environmental exposures. However, it is possible ...